ARRIVAL OF A NEW DIETARY SUPPLEMENT ON HORIZON GARCINI CAPSULESA PURELY 100% FRUITFUL HERBAL TREATMENT OBTAINED FROM GARCINIA CAMBOGIAGARCINI CAPSULES OFFERS CONTROL OVER OBESITY PROBLEM DUE TO ITS MEDICINAL PROPERTIES.OBESITY:- A CONDITION WHICH AFFECTS MILLIONS OF PEOPLE WORLDWIDE IT SUBSTANIALLY RAISES THEIR RISK OF MORBIDITY FROM HYPERTENSION, DYSLIPIDEMIA, TYPE 2 DIABETES, CORONARY HEART DISEASES, CEREBRAL STROKE, GALL BLADDER DISEASE, OSTEOARTHRITIS AND MANY MORE.OBESITY IS DEFINED AS HAVING ABODY MASS INDEX (BMI) OF 30KG/m2 IT DEVELOPS FROM INTERACTION OF GENETICS & ENVIRONMENT.RECENT STUDIES INDICATE THAT THE PREVALENCE OF OBESITY HAS INCREASED FROM 12% IN 1991 TO 18% IN 1998.MANY OBESITY THERAPIES HAVE BEEN FOUND TO BE INEFFECTIVE OVER THE LONG TERM AND IN SOME CASES HAVE LED TO HARMFUL EFFECTS.THIS HAS LED MANY TO LOOK FOR THE NATURAL DIET AIDS THOUGHT TO BE SAFER WITHOUT ANY UNTOWARD SIDE EFFECTS.HERBAL PRODUCTS HAVE BEEN FOUND TO BE VERY EFFECTIVE IN THE MANAGEMENT OF OBESITY AND ASSOCIATED DISORDERS.GARCINIA CAMBOGIA &＃8211; IS ONE SUCH AGENT THAT HAS BEEN SUBJECT OF SIGNIFICANT CLINICAL INTEREST & SCIENTIFIC STUDIES.WEIGHT GAIN OCCURS AFTER BODY’S CAPACITY FOR GLYCOGEN STORAGE IS REACHED. AT THIS POINT, GLUCOSE FROM EXCESSIVE CALORIE INTAKE IS CONVERTED INTO ACETYL COA VIA A METABOLIC PATHWAY INVOLVINH ATP CITRATE LYASE AND THEN INTO FAT MOLECULES WHICH ARE STORED IN FAT CELLS (ADIPOSE).HCA INHIBITS THIS PROCESS BY BINDING TO ATP &＃8211; CITRATE LYASE TO REDUCE THE PRODUCTION OF THE ACETYL COA THUS REDUCING THE BODY’S PRODUCTION OF FAT AND CHOLESTEROL. HCA ALSO INCREASES THE ABILITY OF LIVER AND MUSCLES TO SYNTHESIS & STORE GLYCOGEN, THEREBY SUPPRESSING APPETITE.MECHANISM OF ACTION:- GARCINIA CAMBOGIA EXTRACT IS THE CALCIUM SALT OF HYDROXY CITRIC ACID (HCA) WHICH IS OBTAINED FROM WATER EXTRACT OF GARCINIA CAMBOGIA FRUIT. IT IS USED AS AN APPETITE SUPPRESSANT AND TO INHIBITSYNTHESI